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Real  hope for two children (My Daughter) Fund
1 nonprofit
Real hope for two children (My Daughter) Fund
My daughter Isis and another child, Seppe, suffer from a rare and severe heart disease (restrictive cardiomyopathy caused by a TNNI3 mutation). Currently, there is no effective treatment available. Over the past period, alongside my work at ASML, I have been fully committed to finding a solution. This has led to an important breakthrough: we are now collaborating with a professor in the US who has developed a promising peptide — a molecule based on a natural protein from the human body — that directly targets the underlying disease mechanism. For the first time, there is real hope on the horizon. We are currently working together with UMC Utrecht to test this peptide on heart cells derived from Isis and Seppe — a next step that is being made possible in part thanks to earlier support and contributions, including from many of you within ASML. These living heart cells will allow us to test and compare different treatment approaches, including gene therapy. However, gene therapy falls into a more complex regulatory category, requiring substantial time and investment. As a result, it is less likely to deliver a treatment within a timeframe that could benefit our children. The next step is the critical bottleneck: • preclinical studies to determine dosage and toxicity (including animal studies) These studies are essential and expensive, but required to move safely toward treatment in patients. • If these two studies are successful, a unique opportunity opens up: we can potentially proceed via an accelerated pathway (Named Patient / compassionate use) to treat Isis and Seppe. • If all goes well, treatment could be possible within ~1.5 years. Importantly, the impact may extend far beyond these two children: if this treatment proves successful, it could open the door to a therapy for diastolic heart failure with preserved ejection fraction (HFpEF) — a condition affecting millions of people worldwide for which there is currently no effective solution. For us, this is not theoretical. This is currently the only realistic path toward a treatment. To support this work, we use Stichting Tikkertje, which was originally established to fund gene therapy research and is now also supporting this new and promising approach. 💡 Your ASML donation will directly contribute to enabling these crucial next steps, including the testing on patient-derived heart cells and the required preclinical studies. We are in a race against time. Every contribution — no matter how small — helps us move faster. More information: www.stichtingtikkertje.nl
失家兒少繼續就學      Education Continuation Program for Youth Without Family Care Fund
1 nonprofit
失家兒少繼續就學 Education Continuation Program for Youth Without Family Care Fund
失家兒少繼續就學計畫 對多數青少年來說,15 至 18 歲應該是懷抱夢想、想像未來的年紀。 然而,對一些曾在育幼院長大的孩子而言,人生的道路卻截然不同。 當他們離開安置體系後,往往不再有家庭的支持,必須獨自面對租屋、工作與生活開銷。在這樣的處境下,繼續升學往往成了一件「奢侈的事」,而學費更是沉重的負擔。對失家兒少而言,追求升學夢想,有時意味著必須在 生存與學習之間做出艱難選擇。 透過 「失家兒少繼續就學計畫」,我們希望確保這些努力自立的孩子,不會因為經濟困難而被迫放棄自己的未來。 為什麼您的支持很重要 教育,是翻轉貧困最重要的力量之一。 如果缺乏支持,許多離開育幼院的年輕人只能選擇休學工作,勉強維持生活;但若能獲得適當的協助,他們就能繼續完成學業,為未來建立更穩定、自立的人生。您的支持,能守護孩子 受教育的權利,也讓他們有機會勇敢追尋屬於自己的未來。 您的捐款將如何幫助孩子 本計畫募得的經費,將用於提供失家兒少在求學過程中的重要支持,包括: • 學費與學雜費補助 • 書籍與學習相關教材費用 • 課業輔導與學習支持 • 社工專業陪伴與就學輔導 社工將陪伴每一位孩子,協助他們在生活困境中仍能穩定就學,或在中斷學習後重新回到校園。我們希望透過這些支持,讓經濟困難不再成為阻斷孩子學習機會的原因。 您的支持,能帶來改變 您的每一份捐款,都能為孩子帶來實質幫助: • 500 元 可支持書籍與學習教材費用 • 1,000 元 可提供課業輔導與學習支持 • 2,000 元 可協助一名學生的重要學費支出 每一份善意都在幫助一位孩子繼續完成學業,走向更穩定、充滿希望的未來。 Support Education for Youth Without Family Care For most teenagers, ages 15–18 are a time to dream about the future. But for some young people who grew up in residential care, life looks very different. Once they leave the care system, many no longer have family support. They must find housing, work, and manage daily expenses on their own. In these circumstances, continuing their education can feel like a luxury, and tuition becomes a heavy burden. For youths without family care, pursuing higher education often means facing a choice between survival and studying. Through the Education Continuation Program for Youth Without Family Care of Chinese Children’s Home and Shelter Association (CCSA), we help ensure that these young people do not have to give up their dreams simply because of financial hardship. Why Your Support Matters Education is one of the most powerful ways to break the cycle of poverty. Without support, many youth leaving care are forced to suspend their studies in order to work and survive. With the right assistance, however, they can stay in school, complete their education, and build stable, independent lives. Your support can help protect their right to learn and give them the chance to pursue the future they deserve. How Your Donation Helps Funds raised through this program will support youth without family care by providing: • Tuition and school-related fees • Books and learning materials • Tutoring and academic support • Professional social work guidance to support continued education Our social workers work closely with each young person to help them stay in school or return to their studies when life challenges arise. Together, we can ensure that financial hardship does not take away their opportunity to learn and grow. Your Impact Your generosity can make a meaningful difference: • TWD 500 helps provide books and learning materials • TWD 1,000 supports tutoring and academic assistance • TWD 2,000 helps cover tuition and essential education costs for a student Every donation helps a young person continue their education and move closer to a stable and hopeful future.
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